Journal
BIOCHEMISTRY-MOSCOW
Volume 67, Issue 10, Pages 1136-1144Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1023/A:1020963207320
Keywords
disaccharide nucleosides; oligonucleotides; structure; physicochemical and substrate properties; affinity modification; enzymes of nucleic acid metabolism
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The main structural features of an important group of natural compounds, disaccharide nucleosides, are reviewed. The synthesis and properties of modified oligonucleotides on their basis as well as the methods of introduction of reactive aldehyde groups are described. The last part is devoted to the application of these compounds for studies of enzymes of nucleic acid metabolism.
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