Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 6, Issue 5, Pages 612-618Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1367-5931(02)00364-2
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Electrons migrate over long distances along the DNA in a multistep hopping process where the rate of each step depends strongly upon its length. The efficiency of this process is not only determined by the electron transfer rates but also by competing reactions with water, in which the charge carriers are trapped. Because electron transfer through DNA can occur under the conditions of oxidative stress, biological consequences are highly likely. In addition, it has been observed that some DNA-binding enzymes influence this charge transport. The question of whether DNA is a suitable material for nanolelectronic devices remains unanswered.
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