Journal
TRENDS IN BIOCHEMICAL SCIENCES
Volume 27, Issue 10, Pages 497-500Publisher
CELL PRESS
DOI: 10.1016/S0968-0004(02)02181-3
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A novel FAD-binding domain, BLUE exemplified by the N-terminus of the AppA protein from Rhodobacter sphaeroides, is present in various proteins, primarily from Bacteria. The BLUF domain is involved in sensing blue-light (and possibly redox) using FAD and is similar to the flavin-binding PAS domains and cryptochromes. The predicted secondary structure reveals that the BLUF domain is a novel FAD-binding fold.
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