Journal
NATURE REVIEWS IMMUNOLOGY
Volume 2, Issue 10, Pages 760-772Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nri913
Keywords
-
Categories
Ask authors/readers for more resources
The thymus is the main producer of alphabeta T cells and is, therefore, crucial for a normal immune system. The intrathymic developmental pathway of human alphabeta T cells has now been delineated. The production of new T cells by the thymus decreases With age, and the thymus was thought to be redundant in adults once the peripheral T-cell pool has been formed early in life. However, recent work has shown that the thymus can function even at an advanced age. Research into the production of T cells in clinical settings that are associated with loss of T cells in the periphery has sparked renewed interest in the function of the human thymus.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available