Journal
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Volume 24, Issue 10, Pages 965-969Publisher
JOHN WILEY & SONS INC
DOI: 10.1002/hed.10118
Keywords
branchiogenic carcinoma; branchial cleft carcinoma; occult primary; lateral cervical cyst
Categories
Ask authors/readers for more resources
Background. The development of an invasive squamous cell carcinoma within a lateral cervical cyst as a result of malignant transformation of the epithelium is considered a rare circumstance. The existence of this entity is a source of controversy in light of the differential diagnosis, which includes a cervical metastasis from an unknown primary carcinoma (CUP-syndrome). Apart from site, histologic findings, and follow-up, the principal diagnostic criterion for lateral cervical cyst carcinoma is the histomorphologic demonstration of transition of the benign epithelium into invasive squamous cell carcinoma. Although numerous case reports of this entity exist, carcinoma in situ in a lateral cervical cyst has been reported in only five cases thus far. Method. In this context, we present the case of a 44-year-old patient with a 7-month history of cervical swelling. Results. After diagnostic extirpation of the tumor, histologic findings were consistent with a lateral branchial cyst with high-grade dysplasia and carcinoma in situ of the squamous epithelial lining. Conclusion. This case of a premalignant lesion within a lateral branchial cyst (ie, carcinoma in situ) supplies the missing link and adds credibility to the concept of primary branchiogenic carcinoma. (C) 2002 Wiley Periodicals, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available