Journal
NATURE
Volume 419, Issue 6907, Pages 583-586Publisher
NATURE PORTFOLIO
DOI: 10.1038/nature01079
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Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.
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