Journal
MOLECULAR BRAIN RESEARCH
Volume 106, Issue 1-2, Pages 151-156Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0169-328X(02)00439-4
Keywords
granule cell; cerebellum; HMG-box
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We describe here the identification and characterization of a new gene, Cic, in both human and mouse genomes. These are orthologs of the Drosophila gene capicua, and represent a new subfamily of the HMG-box superfamily. Expression of the Cic gene is predominantly restricted to immature granule cells in the cerebellum, hippocampus and olfactory bulb in the CNS. This gene is therefore implicated in CNS development, in particular in granule cell development. (C) 2002 Elsevier Science B.V. All rights reserved.
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