Preparation of solid-supported lipid bilayers by spin-coating

A new method to deposit lipid bilayers on solid substrates by spin-coating of lipid solutions is presented, leading to highly aligned and homogeneous bilayers probably nucleating at the interface. Importantly, the total number of bilayers can be controlled by the deposition parameters. The samples have been characterized by X-ray reflectivity, both at partial and at full hydration in the presence of excess water.