Journal
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Volume 298, Issue 1, Pages 75-79Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/S0006-291X(02)02390-2
Keywords
Streptococcus mutans; extracellular matrix molecules; antigen I/II; fibrinogen
Categories
Funding
- NCRR NIH HHS [RR03032] Funding Source: Medline
- NHLBI NIH HHS [T32-HL07737, HL03322] Funding Source: Medline
- NIDCR NIH HHS [DE10595] Funding Source: Medline
Ask authors/readers for more resources
We have determined the ability of Streptococcus mutans cells to bind to extracellular matrix (ECM) molecules and fibrinogen. S. mutans cells were found to bind fibronectin, laminin, collagen type I, and fibrinogen. An isogenic S. mutans strain with a defect in the expression of the major surface protein of S. mutans, antigen I/II, possessed a reduced ability to bind fibronectin, collagen, and fibrinogen but not laminin, suggesting that antigen I/II contributes during pathological processes to the interaction of S. mutans cells with fibronectin, collagen type I, and fibrinogen. (C) 2002 Elsevier Science (USA). All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available