4.4 Article

Enantioselective hydrogenation of enamides catalyzed by chiral rhodium-monodentate phosphite complexes

Journal

TETRAHEDRON LETTERS
Volume 43, Issue 44, Pages 7941-7943

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)01838-5

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Chiral monophosphites derived from BINOL are cheap and efficient ligands in the Rh-catalyzed hydrogenation of N-acyl enamides, providing amines with high degrees of enantioselectivity (up to 97.0% ee). (C) 2002 Elsevier Science Ltd. All rights reserved.

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