Journal
JOURNAL OF NATURAL PRODUCTS
Volume 65, Issue 11, Pages 1727-1730Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np020090g
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Three new terpenoids, 1a-3a, and the known metabolites atomaric acid, stypoquinonic acid, and 5'a-desmethyl-5'-acetylatomaric acid have been isolated from the tropical brown alga Stypopodium zonale. The structures and relative stereochemistry of the methyl ester of 1a-3a were determined by spectral methods. The methyl ester of 3a exhibits in vitro cytotoxic activity against human lung and colon carcinoma.
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