Journal
PHARMACOGENOMICS
Volume 3, Issue 6, Pages 809-822Publisher
FUTURE MEDICINE LTD
DOI: 10.1517/14622416.3.6.809
Keywords
expression profiling; laser capture microscopy; patch clamp; promoter driven reporter transgenic; single cell PCR
Categories
Ask authors/readers for more resources
A fundamental challenge in biology is to correlate physiology with gene expression in specific cell types. This can only be achieved by understanding gene expression at the level of the single cell because, in many systems, each cell has the capacity to express a unique set of genes. Therefore, each cell can be considered to be functionally distinct. A clearer understanding of gene expression differences at such a discrete level provides an opportunity to develop drugs with more targeted pharmacologies or with decreased side effects.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available