Journal
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
Volume 81, Issue 11, Pages S127-S147Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00002060-200211001-00014
Keywords
physical activity; stress-strain; skeletal muscle plasticity; myogenesis; dystrophy
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Funding
- NINDS NIH HHS [NS16333] Funding Source: Medline
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Those factors that seem to play some role in inducing adaptations of skeletal muscle in vivo are discussed. The role of myogenesis in maintaining and repairing muscle during atrophic and hypertrophic states is discussed, including pointing out that the modulation of myonuclear number is one means of adapting to varying chronic levels of neuromuscular activity. Finally, we point out the potential consequences of muscle atrophy on the control of movement and the susceptibility to fatigue.
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