Journal
PHYTOTHERAPY RESEARCH
Volume 16, Issue 7, Pages 700-702Publisher
JOHN WILEY & SONS LTD
DOI: 10.1002/ptr.1019
Keywords
rice bran; anti-stress; anti-fatigue; Saccharomyces cerevisae
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The anti-stress and anti-fatigue effects of a hot water extract of fermented rice bran (FRB) were investigated with Saccharomyces cerevisae IFO 2346 on rats or mice. Oral administration (1 g/kg/day) of a hot water extract of FRB inhibited major changes in weight of the adrenal, thymus, spleen and thyroid, showing the anti-stress effect. A hot water extract of FRB also inhibited the increase of GPT and LDH activity, cholesterol and serum glucose levels. Administration (1 g/kg/day) for 2 weeks significantly prolonged the swimming time, resulting in an increase of the anti-fatigue effect. From these results, it can be considered that FRB has an anti-stress and anti-fatigue effect. Copyright (C) 2002 John Wiley Sons, Ltd.
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