Journal
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Volume 94, Issue 5, Pages 401-405Publisher
SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/S1389-1723(02)80216-X
Keywords
Enterococcus faecalis; Trichophyton; tinea; antifungal activity; lactic acid bacteria; organic acid; herb
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The fermentation product of herbs by lactic acid bacteria (FHL), in which Enterococcus faecalis THIO predominated, was assayed for antifungal activity against tinea. The antifungal activity of FHL was as high as that of a synthetic fungicide. Autoclaving FHL did not reduce its antifungal activity, whereas neutralizing it did. The results suggested that nonproteinaceous compounds or organic acids in FHL could inhibit the growth of the dermatophyte tinea under low-pH conditions, and that malonic acid and acetic acid could have especially high antifungal activity against tinea.
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