Journal
JOURNAL OF VIROLOGY
Volume 76, Issue 21, Pages 11166-11171Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.76.21.11166-11171.2002
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The influenza A virus nonstructural NS1 protein is known to modulate host cell gene expression and to inhibit double-stranded RNA (dsRNA)-mediated antiviral responses. Here we identify NS1 as the first viral protein that antagonizes virus- and dsRNA-induced activation of the stress response-signaling pathway mediated through Jun N-terminal kinase.
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