Frequency of cytokine polymorphisms in populations from Western Europe, Africa, Asia, the Middle East and South America

PCR-SSOP identification procedures for IL-2, IL-6, IL-10, TNF-alpha and TNF-beta cytokine polymorphisms have been developed. Application of the procedures to a range of diverse geographically distributed populations has identified ethnic differences within the groups studied. Five populations were investigated, Northern Ireland, South African Zulu, Omani, Singapore Chinese and Mexican Mestizos. (C) American Society for Histocompatibility and Immunogenetics, 2002. Published by Elsevier Science Inc.