Journal
BLOOD CELLS MOLECULES AND DISEASES
Volume 29, Issue 3, Pages 261-266Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1006/bcmd.2002.0566
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- NICHD NIH HHS [HD 29934] Funding Source: Medline
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EAAC1 is a widely expressed protein which transports anionic amino acids in a Na+-dependent fashion. Rat erythrocytes have generally been thought to be impermeant to anionic amino acids. Utilizing immunoelectron microscopy, we have demonstrated the presence of EAAC1-immunoreactive protein within rat erythrocytes. Immunoblotting revealed the presence of an approximately 60-kDa protein, consistent with EAAC1, in erythrocyte membranes. Specificity was confirmed by peptide competition. In conclusion, EAAC1 is expressed in rat erythrocytes. (C) 2002 Elsevier Science (USA).
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