Journal
INFECTION AND IMMUNITY
Volume 70, Issue 11, Pages 6456-6459Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.70.11.6456-6459.2002
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Funding
- NHLBI NIH HHS [HL 59558] Funding Source: Medline
- NIAID NIH HHS [AI 27243, N01AI95383, K08 AI001581, R01 AI027243, K08 AI 01581, P30 AI036219, AI 95383, AI-36219] Funding Source: Medline
- NIGMS NIH HHS [GM 36387, R01 GM036387] Funding Source: Medline
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Extracellular ATP at millimolar concentrations inhibits growth of mycobacteria in human macrophages. Whether T cells can produce sufficient ATP is unknown. CD4(+) and CD8(+) T cells did not release sufficient ATP through either degranulation or lysis of bystander cells to restrict growth of Mycobacterium bovis BCG in monocytes.
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