Journal
TETRAHEDRON LETTERS
Volume 43, Issue 46, Pages 8235-8239Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)02036-1
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Various pyrimido[4,5-b]indoles and benzo[4,5]furo[2,3-d]pyrimidines were synthesized via a palladium-catalyzed intramolecular arylation of pyrimidine substrates. Thus, 4-aryloxy- or 4-anilino-5-iodopyrimidines were treated with Pd(OAc)(2)(PPh3)(2) and base in DMF to give the regioselective cyclized heterocycles. (C) 2002 Elsevier Science Ltd. All rights reserved.
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