4.8 Article

Microwave-assisted solid-phase synthesis of peptoids

Journal

ORGANIC LETTERS
Volume 4, Issue 23, Pages 4057-4059

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0267578

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Funding

  1. NCI NIH HHS [1R21 CA 093287-01] Funding Source: Medline

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[GRAPHICS] Microwave irradiation reduces the reaction time for the solid-phase synthesis of peptoids. Under these conditions, coupling of each residue requires only 1 min. The purity and yields of peptoids synthesized in this way are as good as or better than those achieved using standard methods.

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