Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 22, Pages 2620-2621Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b208288h
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An unprotected 16 residue peptide containing a C-terminal thioester and an N-terminal selenocysteine residue efficiently cyclizes in the presence of thiophenol; subsequent reduction, elimination or alkylation of the selenol yields modified cyclic peptides with alanine, dehydroalanine or a non-natural amino acid at the site of ligation.
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