4.8 Article

Stereospecific synthesis of highly substituted skipped dienes through multifunctional palladium catalysis

Journal

ORGANIC LETTERS
Volume 4, Issue 24, Pages 4317-4320

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0269594

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graphic Multifunctional palladium catalysis is utilized in the one-pot stereocontrolled synthesis of tetrasubstituted alkenes. The homogeneous palladium dihalide catalyst utilized for bromo-/chloroallylation of alkynes is then reused in situ for a subsequent Suzuki cross-coupling reaction.

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