Journal
ASTROBIOLOGY
Volume 2, Issue 4, Pages 371-381Publisher
MARY ANN LIEBERT INC
DOI: 10.1089/153110702762470482
Keywords
membranes; amphiphiles; self-assembly; prebiotic
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Organic compounds are synthesized in the interstellar medium and can be delivered to planetary surface's such as the early Earth, where they mix with endogenous species. Some of these compounds are. amphiphilic, having polar and nonpolar groups on the same molecule. Amphiphilic compounds spontaneously self-assemble into more complex structures such as bimolecular layers, which in turn form closed membranous vesicles. The first forms of cellular life required self-assembled membranes that were likely to have been produced from amphiphilic compounds on the prebiotic Earth. Laboratory simulations show that such vesicles readily encapsulate functional macromolecules, including nucleic acids and polymerases. The goal of future investigations will be to fabricate artificial cells as models of the origin of life.
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