Journal
JOURNAL OF NATURAL PRODUCTS
Volume 65, Issue 12, Pages 1936-1938Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np020250o
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Sodium 1-(12-hydroxy)octadecanyl sulfate (1) was isolated from a marine tunicate as a matrix metalloproteinase 2 (MMP2) inhibitor.(1) The structure was elucidated by a combination of spectroscopic and chemical methods. Compound 1 inhibited MMP2 with an IC50 value of 9.0 mug/mL.
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