Journal
MEDICAL PHYSICS
Volume 29, Issue 12, Pages 2788-2798Publisher
AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS
DOI: 10.1118/1.1521122
Keywords
proton radiotherapy; dosimetry; laser-proton acceleration; laser-plasma interaction
Funding
- NCI NIH HHS [CA78331] Funding Source: Medline
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In this article we present the results of particle in cell (PIC) simulations of laser plasma interaction for proton acceleration for radiation therapy treatments. We show that under optimal interaction conditions protons can be accelerated up to relativistic energies of 300 MeV by a petawatt laser field. The proton acceleration is due to the dragging Coulomb force arising from charge separation induced by the ponderomotive pressure (light pressure) of high-intensity laser. The proton energy and phase space distribution functions obtained from the PIC simulations are used in the calculations of dose distributions using the GEANT Monte Carlo simulation code. Because of the broad energy and angular spectra of the protons, a compact particle selection and beam collimation system will be needed to generate small beams of polyenergetic protons for intensity modulated proton therapy. (C) 2002 American Association of Physicists in Medicine.
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