Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 40, Issue 12, Pages 4544-4546Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.40.12.4544-4546.2002
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We used a sample of Staphylococcus aureus strains that are carried by humans and that are representative of the natural population of S. aureus strains in order to assess the value of multilocus sequence typing (MLST), pulsed-field gel electrophoresis, randomly amplified polymorphic DNA analysis, and phage typing as epidemiological tools. Only MLST was able to define clonal complexes unambiguously. All DNA-based typing approaches achieved a high degree of agreement, implying phylogenetic concordance, but predicted epidemiological associations with variable accuracy.
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