Journal
MICROBES AND INFECTION
Volume 4, Issue 15, Pages 1505-1512Publisher
EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/S1286-4579(02)00033-3
Keywords
NK cell; cytomegalovirus; major histocompatibility complex
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Funding
- NCI NIH HHS [CA89294, CA89189] Funding Source: Medline
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Natural killer (NK) cells can mount an immediate response against viral infection, secreting cytokines and killing virus-infected cells. However, viruses have devised strategies to avoid immune detection. Here, we discuss NK cell recognition of viruses and propose that viruses may provide the evolutionary pressure causing the diversification of the NK cell receptors. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
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