Journal
BIOLOGICAL TRACE ELEMENT RESEARCH
Volume 90, Issue 1-3, Pages 25-30Publisher
HUMANA PRESS INC
DOI: 10.1385/BTER:90:1-3:25
Keywords
children; endemic goiter; iodine deficiency; selenium deficiency; insulin-like growth factor-I; insulin-like growth factor binding; protein-3
Ask authors/readers for more resources
Serum insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) levels were investigated in 31 children living in an endemic goiter area and 33 healthy subjects living in an nonendemic area. Serum lGF-I and IGFBP-3 levels of iodine- and selenium deficient children were found to be lower than those of control subjects (p<0.001). There was a positive correlation between the IGF-I with chronological age and body mass index. There was also positive correlation between the lGF-I and IGFBP-3. No significant difference was found between the goitrous and nongoitrous children. These results suggest that IGF-I and IGFBP-3 levels are affected by thyroid dysfunction as a result of iodine and selenium deficiency. However, IGF-I and IGFBP-3 levels are not associated with goiter.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available