3.8 Article

Structure of linear double-stranded deoxyribonucleic acid adsorbed on Cu(111) surfaces: A low-temperature scanning tunneling microscopy study

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INST PURE APPLIED PHYSICS
DOI: 10.1143/JJAP.41.7510

Keywords

deoxyribonucleic acid (DNA); scanning tunneling microscopy (STM); Cu(111); pulse injection; poly(dA-dT)-poly(dA-dT); poly(dG-dC)-poly(dG-dC); high-resolution analysis

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We have obtained high-resolution scanning tunneling microscopy (STM) images of poly(dA-dT)-poly(dA-dT) and poly(dG-dC)-poly(dG-dC) adsorbed on Cu(111) substrates. STM revealed that the two deoxyribonucleic acid molecules have different adsorbed structures and topographic heights. We concluded that the observed structural differences originate from the inherent differences in the stability of the adenine-thymine (A-T) and guanine-cytosine (G-C) base pairs.

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