Journal
CURRENT OPINION IN PHARMACOLOGY
Volume 2, Issue 6, Pages 723-729Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1471-4892(02)00232-1
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It has become apparent in recent years that the glucocorticoid receptor is not a simple on/off switch, but instead orchestrates Subtle and complex interactions between large numbers of proteins. This more sophisticated understanding awaits a unifying concept that will explain mechanisms of glucocorticoid resistance and allow new approaches to enhancing sensitivity.
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