4.3 Article

Effect of dried fruits of Carica papaya LINN on hepatotoxicity

Journal

BIOLOGICAL & PHARMACEUTICAL BULLETIN
Volume 25, Issue 12, Pages 1645-1646

Publisher

PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/bpb.25.1645

Keywords

Carica papaya; CCl4; hepatoprotective activity

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Ethanol and aqueous extracts of Carica papaya has been evaluated for its anti hepatotoxic activity. The ethanol and aqueous extracts of Carica papaya showed remarkable hepatoprotective activity against CCl4 induced hepatotoxicity. The activity was evaluated by using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase, total bilirubin and gamma glutamate transpeptidase (GGTP). The histopathological changes of liver sample was compared with respect to control.

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