Journal
SYNLETT
Volume -, Issue 12, Pages 1954-1965Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2002-35576
Keywords
iridium complex; catalysis; pi-allyl iridium; iridacyclopentadiene; allylic esters; alkynes
Categories
Ask authors/readers for more resources
Two different synthetic reactions catalyzed by an iridium complex are discussed. The first is allylic alkylation and allylic amination. This reaction proceeds via a pi-allyl iridium intermediate. The selectivity strongly depends on the structure of the allylic esters. Highly branched product-selective allylic substitution and highly Z-selective allylic substitution were achieved. The selectivities of allylic substitution described here have not been achieved in previous studies with other transition metal complexes. The second reaction is [2+2+2] cycloaddition of alpha,omega-diynes with monoynes. This reaction proceeds via iridacyclopentadiene and tolerates various functional groups. Functionalized monoynes can be used. These results show that an iridium complex can be a useful catalyst for carbon-carbon and carbon-heteroatom bond formation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available