Journal
JOURNAL OF NATURAL PRODUCTS
Volume 65, Issue 12, Pages 1798-1801Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np020275n
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Two bromotyrosine alkaloids, purealidin S (2) and purpuramine J (5), were isolated from the Fijian marine sponge Druinella sp. Eight known bromotyrosine compounds were also isolated. This is the first report of a bromotyrosine N-oxide containing alkaloid. These two compounds were found to have moderate cytotoxic activity. In addition, bioassay data for the eight known bromotyrosine metabolites are reported.
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