Comparison of methods of interpretation of checkerboard synergy testing

Four different methods for interpreting the results of checkerboard synergy testing were compared by applying each to a set of synergy study data. Statistically significant differences in synergy were detected among methods (% synergy ranged from 10 to 83%). As interpretations were found to vary widely based upon method, one should be aware of this in interpreting the relevant literature. (C) 2002 Elsevier Science Inc. All rights reserved.