Journal
BRITISH JOURNAL OF DERMATOLOGY
Volume 147, Issue 6, Pages 1249-1253Publisher
BLACKWELL PUBLISHING LTD
DOI: 10.1046/j.1365-2133.2002.05039.x
Keywords
allograft; cultured epidermal autograft; febrile ulceronecrotic Mucha-Habermann disease; pityriasis lichenoides et varioliformis acuta
Categories
Ask authors/readers for more resources
We report a case of febrile ulceronecrotic Mucha-Habermann disease (FUMHD) in a 21-year-old man. This disease is a severe form of pityriasis lichenoides et varioliformis acuta (PLEVA) and is characterized by the sudden onset of diffuse ulcerations associated with high fever and systemic symptoms. It is sometimes lethal especially in elderly patients. In the present case, intense generalized maculopapular erythematous plaques with central necrosis developed progressively in association with a high fever. Initial treatment with systemic betamethasone had been unsuccessful and the skin lesions, which covered about 50% of the body surface, became severely ulcerated. Although the development of new lesions had ceased spontaneously, widespread ulceration of the skin remained. Debridement of the necrotic skin and skin grafting using cultured epidermal autografts and meshed allografts of cadaver skin led to prompt reepithelization.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available