Journal
JOURNAL OF THEORETICAL BIOLOGY
Volume 219, Issue 3, Pages 281-290Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1006/jtbi.2002.3122
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Funding
- NIAID NIH HHS [AI24424] Funding Source: Medline
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Pulsed characters are temporary biochemical, cellular, or structural changes produced in response to environmental or biotic challenge. For example, response to parasitic attack develops as a pulse of defensive chemicals or cells that typically decay after the parasite has been controlled. Almost all theories for the genetic variability of characters assume measurements on static characters. This paper presents theoretical tools to examine optimal control variables for pulsed characters and the expected level of genetic variability in those control variables. The example of host immune response to parasitic attack is used to develop the theory. (C) 2002 Elsevier Science Ltd. All rights reserved.
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