4.4 Article

Total synthesis of myriocin

Journal

TETRAHEDRON LETTERS
Volume 43, Issue 51, Pages 9361-9363

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)02371-7

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A concise, stereocontrolled synthesis of myriocin was achieved. Key features involve diastereoselective oxazoline formation catalyzed by palladium(0), MgBr2-promoted allylic stannane addition, and palladium(0)-catalyzed coupling of a vinyl iodide with an organozinc reagent. (C) 2002 Elsevier Science Ltd. All rights reserved.

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