Journal
VACCINE
Volume 20, Issue -, Pages A28-A31Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S0264-410X(02)00384-5
Keywords
tumor-derived exosomes; tumor rejection antigens; cancer vaccines
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Exosomes are small vesicles released by a broad array of hematopoietic cells. Previous studies showed that exosomes released by antigen loaded dendritic cells induce immune-mediated anti-tumor response in mice. Here, we will describe the biochemical properties of tumor-derived exosomes and, their pre-clinical activity as cancer vaccines. (C) 2002 Elsevier Science Ltd. All rights reserved.
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