4.4 Article

A direct synthesis of nitriles and amides from aldehydes using dry or wet alumina in solvent free conditions

Journal

TETRAHEDRON
Volume 58, Issue 52, Pages 10323-10328

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4020(02)01417-5

Keywords

graphite; dry-alumina; wet-alumina; aldehyde

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An efficient and simple procedure for the direct conversion of aldehydes into the corresponding nitriles with (NH2OHHCl)-H-./dry Al2O3/MeSO2Cl or amides with (NH2OHHCl)-H-./wet Al2O3/MeSO2Cl are studied. (C) 2002 Elsevier Science Ltd. All rights reserved.

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