4.4 Article

A direct synthesis of denbinobin

Journal

TETRAHEDRON LETTERS
Volume 43, Issue 52, Pages 9597-9599

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)02411-5

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Denbinobin was made in seven steps from quinone 3. The cyclization of aldehyde 12 using P-4-tBu and the oxidation of a hindered alcohol with MnO2 were key steps. (C) 2002 Elsevier Science Ltd. All rights reserved.

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