2-Deoxy-2-iodo-β-glucopyranosyl fluorides:: Mild and highly stereoselective glycosyl donors for the synthesis of 2-deoxy-β-glycosides from β-hydroxy ketones

2-Deoxy-2-iodo-beta-glucopyranosyl fluoride 14 is a highly stereoselective glucopyranosyl donor that may be activated under mild conditions. Application of this new glycosyl donor to the glycosidation reactions of a variety of acceptors including beta-hydroxy ketones affords beta-glycosides with high efficiency and stereoselectivity.