Journal
JOURNAL OF INFECTIOUS DISEASES
Volume 187, Issue 2, Pages 315-319Publisher
UNIV CHICAGO PRESS
DOI: 10.1086/346054
Keywords
-
Categories
Funding
- NCI NIH HHS [R01 CA24553] Funding Source: Medline
- NIAID NIH HHS [U01 AI37984, U01 AI35041, T32 AI 07487, R01 AI41870] Funding Source: Medline
Ask authors/readers for more resources
Proteins may serve as ideal CD8(+) T cell immunogens for human immunodeficiency virus type 1 (HIV-1) if they can be delivered to and processed through the human leukocyte antigen class I pathway. This study shows that human blood monocyte-derived dendritic cells loaded with liposome-complexed HIV-1 proteins and matured with CD40 ligand can prime CD8(+) T cells to HIV-1 in vitro. Whole HIV-1 protein in liposome may be an effective immunogen for HIV-1 vaccine protocols.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available