Journal
TETRAHEDRON LETTERS
Volume 44, Issue 4, Pages 811-814Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)02656-4
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A new strategy for the solid-phase synthesis of unsymmetrical ureas is described. Upon treatment of Kenner safety-catch linker with an isocyanate, followed by TMSCHN2 or iodoacetonitrile and an amine, the corresponding unsymmetrical ureas are released in solution. (C) 2003 Elsevier Science Ltd. All rights reserved.
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