Journal
JOURNAL OF CHROMATOGRAPHY A
Volume 985, Issue 1-2, Pages 303-312Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/S0021-9673(02)01472-3
Keywords
cigarette smoke; pyridines
Ask authors/readers for more resources
A new technique has been developed for the quantitative analysis of pyridines in mainstream cigarette smoke using a GC-MS technique. For analysis, 10 cigarettes are smoked using conditions based on US Federal Trade Commission recommendations. The smoke is collected in a water trap and analyzed using a GC-MS technique. A standard or a fast GC separation can be applied for the analysis. The standard separation was followed by MS detection using selected ion monitoring (SIM) acquisition on a quadrupole instrument. The fast GC was followed by MS detection with total ion acquisition on a time-of-flight instrument. The levels of pyridine depend on the type of cigarette: for a full flavor cigarette pyridine is as high as 18.0 mug/cigarette (cig.), and for an ultra light cigarette is about 3.0 mug/cig. Substituted pyridines vary between 5.0 mug/cig. to 0.1 mug/cig. for a full flavor cigarette, and between 0.2 mug/cig. and a few ng/cig. for an ultra light cigarette. The reproducibility of the technique is very good, with less than 7-8% RSD in both separation procedures for most of the analyzed compounds. (C) 2002 Elsevier Science B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available