4.4 Article

Enantioselective synthesis of D-ribo-(2S,3S,4R)-C18-phytosphingosine using double stereodifferentiation

Journal

TETRAHEDRON LETTERS
Volume 44, Issue 5, Pages 1035-1037

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)02732-6

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An enantio selective synthesis of D-ribo-C-18-phytosphingosine as its tetraacetate derivative 10, starting from D-mannitol and employing the Sharpless asymmetric dihydroxylation reaction on allylic alcohol 6 as the key step, is described. (C) 2003 Elsevier Science Ltd. All rights reserved.

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