4.4 Article

Trifluoroacetophenone as nucleophilic trifluoromethylating reagent

Journal

TETRAHEDRON LETTERS
Volume 44, Issue 5, Pages 1055-1057

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(02)02718-1

Keywords

trifluoroacetophenone; nucleophilic trifluoromethylation; fluorinated compounds; trifluoromethylcarbinol

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Trifluoroacetophenone can be used as nucleophilic trifluoromethylating reagent towards non-enolizable ketones by action of potassium tert-butoxide. (C) 2003 Elsevier Science Ltd. All rights reserved.

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