Journal
THERAPEUTIC APHERESIS AND DIALYSIS
Volume 7, Issue 1, Pages 73-77Publisher
WILEY
DOI: 10.1046/j.1526-0968.2003.00018.x
Keywords
dextran sulfate cellulose column; familial hypercholesterolemia; peripheral arterial disease; focal segmental glomerulosclerosis; systemic lupus erythematosus
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Liposorber is a column used for plasma purification that adsorbs low-density lipoproteins with high selectivity while Selesorb is a column that selectively adsorbs anti-DNA antibodies, anticardiolipin antibodies, and immune complexes. Both columns are packed with carriers. where a dextran sulfate ligand is bound to porous cellulose beads. Liposorber is used to treat familial hypercholesterolemia (FH), peripheral arterial disease (PAD), and focal segmental glomerulosclerosis (FGS): Selesorb is used to treat systemic lupus erythematosus (SLE). Treatment utilizing both columns is being used effectively in patients with refractory disease that is resistant to pharmacotherapy.
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