Journal
JOURNAL OF CLINICAL NEUROPHYSIOLOGY
Volume 20, Issue 1, Pages 54-58Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00004691-200302000-00007
Keywords
transcranial magnetic stimulation; motor evoked potential; intracortical inhibition; intracortical facilitation
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The influence of the intensity of the conditioning stimulus on intracortical inhibition (ICI) and intracortical facilitation (ICF) was assessed in a study using paired-pulse transcranial magnetic stimulation. Interstimulus intervals (ISIs) between conditioning and test stimuli were 3 msec and 13 msec. Latencies and areas of motor evoked potentials in response to the test stimulus were measured in the right extensor carpi radialis muscle. Motor evoked potential areas with ISIs of 3 msec and 13 msec showed a different dependence on the intensity of the conditioning stimulus. In contrast, the changes of motor evoked potential latencies were fairly similar with both ISIs. The findings point to a parallel action of ICI and ICF. Furthermore, the latencies seem to be a more sensitive indicator for ICF action than the size parameters of motor evoked potentials.
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