Journal
STEROIDS
Volume 68, Issue 2, Pages 139-142Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/S0039-128X(02)00173-3
Keywords
17-ketosteroids; corticosteroids; C-17-dihydroxy acetone side chain cleavage; 11 beta-hydroxy-pregn-4-ene-3,17-dione; 4-androstene-3,17-dione; 4-androstene-3,11,17-trione
Ask authors/readers for more resources
A facile and convenient approach to 17-ketosteroids is described. Treatment of steroids containing the C-17-dihydroxy acetone side chain with an excess of sodium methoxide in dry 1,4-dioxane under reflux, affords high yields of the corresponding 17-ketosteroids that are recovered as pure products, without the need of further purification. (C) 2002 Elsevier Science Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
